HistoQuest by TissueGnostics GmbH is a Windows-based image analysis solution for brightfield histology and immunohistochemistry. It enables quantitative, single-cell evaluation of biomarkers directly in tissue context, turning whole-slide images into reproducible data for research and pathology workflows.
Key capabilities:
- Brightfield quantification: Color deconvolution of hematoxylin and common chromogens (e.g., DAB, Fast Red) with measurement of nuclear, cytoplasmic, and membrane signals.
- Single-cell segmentation: Automated detection and delineation of cells in complex, heterogeneous tissues.
- Scoring and statistics: Intensity classification (including H-score–style metrics), cell counts, area measurements, and summary reports.
- Region management: Interactive annotations, regions of interest, and automated analysis of tissue microarrays (TMAs).
- Review and validation: Visual overlays for result verification, quality control tools, and batch processing for high-throughput studies.
- Data export and interoperability: Export of measurements for downstream analysis and support for common whole-slide image formats; integrates with TissueFAXS scanners and workflows.
Typical applications include quantitative IHC biomarker assessment, oncology and immunology research, digital pathology R&D, and standardized TMA scoring. HistoQuest helps replace subjective manual scoring with fast, consistent, and traceable measurements, supporting robust, data-driven decisions across studies and teams.
HistoQuest is developed by TissueGnostics GmbH. The most popular versions of this product among our users are: 1.0, 2.0, 3.0 and 4.0. The name of the program executable file is HistoQuest.exe.
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